We do not sell a positive control for this assay. Purified ALT is available from companies such as Sigma. Alternatively, serum samples could be used, for instance FBS (not heat inactivated).
Andres-Hernando, et al (2020). Deletion of Fructokinase in the Liver or in the Intestine Reveals Differential Effects on Sugar-Induced Metabolic Dysfunction. Cell metabolism, 32(1), 117-127. Assay: alanine transaminase in mouse plasma.
Fang, W. et al (2020). Cathepsin B Deficiency Ameliorates Liver Lipid Deposition, Inflammatory Cell Infiltration, and Fibrosis After Diet-Induced Nonalcoholic Steatohepatitis. Translational research: the journal of laboratory and clinical medicine, 222, 28-40. Assay: alanine transaminase in mouse plasma.
Visitchanakun, P. et al (2020). Gut Leakage Enhances Sepsis Susceptibility in Iron-Overloaded β-thalassemia Mice Through Macrophage Hyperinflammatory Responses. American journal of physiology. Gastrointestinal and liver physiology, 318(5), G966-G979. Assay: alanine transaminase in mouse serum.
Gabra, M. B. I. et al (2020). Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth. Nature Communications, 11. Assay: alanine transaminase in mouse serum.
Jiang, S. et al (2020). Dojuksan ameliorates tubulointerstitial fibrosis through irisin-mediated muscle-kidney crosstalk. Phytomedicine: international journal of phytotherapy and phytopharmacology, 80, 153393. Assay: alanine transaminase in mouse plasma.
Xu, W. et al (2020). LyP-1-Modified Oncolytic Adenoviruses Targeting Transforming Growth Factor β Inhibit Tumor Growth and Metastases and Augment Immune Checkpoint Inhibitor Therapy in Breast Cancer Mouse Models. Human gene therapy, 31(15-16), 863-880. Assay: alanine transaminase in mouse serum.
Shin, M. K., Yang, S. M., & Han, I. S. (2020). Capsaicin suppresses liver fat accumulation in high-fat diet-induced NAFLD mice. Animal cells and systems, 24(4), 214-219. Assay: alanine transaminase in mouse plasma.
Andres-Hernando, A. et al (2020). Sugar causes obesity and metabolic syndrome in mice independently of sweet taste. American journal of physiology. Endocrinology and metabolism, 319(2), E276-E290. Assay: alanine transaminase in mouse serum.
Sae-Khow, K. et al (2020). Pathogen-Associated Molecules from Gut Translocation Enhance Severity of Cecal Ligation and Puncture Sepsis in Iron-Overload β-Thalassemia Mice. Journal of inflammation research, 13, 719-735. Assay: alanine transaminase in mouse serum.
Seo, B. et al (2020). Roseburia spp. Abundance Associates with Alcohol Consumption in Humans and Its Administration Ameliorates Alcoholic Fatty Liver in Mice. Cell host & microbe, 27(1), 25. Assay: alanine transaminase in mouse serum.
Jayaraman, S. et al (2020). Peptidase neurolysin functions to preserve the brain after ischemic stroke in male mice. Journal of neurochemistry, 153(1), 120. Assay: alanine transaminase in mouse plasma.
Abubakar, M. B. The Effects of Honey Administration on Petrol-Induced Oxidative Stress and Hepatotoxicity in Sprague-dawley Male Rats. Assay: alanine transaminase in mouse serum.
Durymanov, M., Permyakova, A., & Reineke, J. (2020). Pre-treatment With PLGA/Silibinin Nanoparticles Mitigates Dacarbazine-Induced Hepatotoxicity. Frontiers in Bioengineering and Biotechnology, 8. Assay: alanine transaminase in mouse serum.
Hay, Charles E., et al (2018). Development and testing of AAV-delivered single-chain variable fragments for the treatment of methamphetamine abuse. PloS one 13.6: e0200060. Assay: Alanine transaminase in mice serum.
Loeser, Konstantin, et al (2018). Protective effect of Casperome, an orally bioavailable frankincense extract, on lipopolysaccharide-induced systemic inflammation in mice. Frontiers in pharmacology 9: 387. Assay: Alanine transaminase in mice serum.
Shivange, Gururaj, et al (2018). A single-agent dual-specificity targeting of FOLR1 and DR5 as an effective strategy for ovarian cancer. Cancer cell 34.2: 331-345. Assay: Alanine transaminase in mice serum.
Akingbasote, James A., et al (2017). Improved hepatic physiology in hepatic cytochrome P450 reductase null (HRN) mice dosed orally with fenclozic acid. Toxicology research 6.1: 81-88. Assay: Alanine transaminase in mice plasma.
Kamerkar, Sushrut, et al (2017). Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer. Nature 546.7659: 498. Assay: Alanine transaminase in mice plasma.
Kim, Soo Hyun, et al (2017). Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition. Autophagy 13.10: 1767-1781. Assay: Alanine transaminase in mice serum.
Seemann, Semjon, Franziska Zohles, and Amelie Lupp (2017). Comprehensive comparison of three different animal models for systemic inflammation. Journal of biomedical science 24.1: 60. Assay: Alanine transaminase in mouse serum.
Sharabi, K et al (2017). Selective chemical inhibition of PGC-1alpha gluconeogenic activity ameliorates type 2 diabetes. Cell 169.1: 148-160. Assay: Alanine transaminase in mice serum.
Vasquez, Kristine O., and Jeffrey D. Peterson (2017). Early detection of acute drug-induced liver injury in mice by noninvasive near-infrared fluorescence imaging. Journal of Pharmacology and Experimental Therapeutics 361.1: 87-98. Assay: Alanine transaminase in mice serum.
Wardah, J. Rahmahani, and T. Sopandi (2017). Effect of Phyllanthus buxifolius Leaf as a Feed Supplement on Liver Function and Haematological Response of Quail (Coturnix coturnix japonica) Challenged with Infectious Newcastle Disease Virus. International Journal of Poultry Science 16: 354-363. Assay: Alanine transaminase in quail serum.
Weis, Sebastian, et al (2017). Metabolic adaptation establishes disease tolerance to sepsis. Cell 169.7: 1263-1275. Assay: Alanine transaminase in mice plasma.
Akingbasote, James A., et al (2016). Hepatic effects of repeated oral administration of diclofenac to hepatic cytochrome P450 reductase null (HRN) and wild-type mice. Archives of toxicology 90.4: 853-862. Assay: Alanine transaminase in mice plasma.
Chaudhry, Kamaljit K., et al (2016). Glutamine supplementation attenuates ethanol-induced disruption of apical junctional complexes in colonic epithelium and ameliorates gut barrier dysfunction and fatty liver in mice. The Journal of nutritional biochemistry 27: 16-26. Assay: Alanine transaminase in mice plasma.
Chen, Yingqing, et al (2016). Synergistic effects of cilostazol and probucol on ER stress-induced hepatic steatosis via heme oxygenase-1-dependent activation of mitochondrial biogenesis. Oxidative medicine and cellular longevity 2016:3949813. Assay: Alanine transaminase in mice serum.
Mir, Hina, et al (2016). Occludin deficiency promotes ethanol-induced disruption of colonic epithelial junctions, gut barrier dysfunction and liver damage in mice. Biochimica et Biophysica Acta (BBA)-General Subjects 1860.4: 765-774. Assay: Alanine transaminase in mice plasma.
Seemann, Semjon, and Amelie Lupp (2016). Administration of AMD3100 in endotoxemia is associated with pro-inflammatory, pro-oxidative, and pro-apoptotic effects in vivo. Journal of biomedical science 23.1: 68. Assay: Alanine transaminase in mouse serum.
Wang, Huafeng, et al (2016). Adiponectin-derived active peptide ADP355 exerts anti-inflammatory and anti-fibrotic activities in thioacetamide-induced liver injury. Scientific reports 6: 19445. Assay: Alanine transaminase in mice serum.
Wang, Huafeng, et al (2016). Plumbagin protects liver against fulminant hepatic failure and chronic liver fibrosis via inhibiting inflammation and collagen production. Oncotarget 7.50: 82864. Assay: Alanine transaminase in mice serum.
Ballester-Lozano GF et al. (2015). Comprehensive biometric, biochemical and histopathological assessment of nutrient deficiencies in gilthead sea bream fed semi-purified diets. Br J Nutr. 114(5):713-26. Assay: alanine aminotransferase enzyme activity in fish.
Dankel S, Degerud E et al (2014). Weight cycling promotes fat gain and altered clock gene expression in adipose tissue in C57BL/6J mice. Am J Physiol Endocrinol Metab. 15;306(2):E210-24. Assay: Alanine transaminase in mice plasma.
Peng M1, Xu S et al (2014). Thermosensitive Injectable Hydrogel Enhances the Antitumor Effect of Embelin in mouse Hepatocellular Carcinoma. J. Pharm. Sci., 103: 965-973. Assay: Alanine transaminase in mouse cell.
Kim HJ, Joe Y et al (2013). Carbon monoxide protects against hepatic ischemia/reperfusion injury via ROS-dependent Akt signaling and inhibition of glycogen synthase kinase 3beta. Oxidative Medicine and Cellular Longevity. 2013: 306421. Assay: Alanine transaminase in mice serum.
Zhang H, Xu H et al (2013). Inhibition of myeloperoxidase decreases vascular oxidative stress and increases vasodilatation in sickle cell disease mice. J Lipid Res. 54(11):3009-15. Assay: Alanine transaminase in mice plasma.
Mani V et al (2012) Effects of the Total Alkaloidal Extract of Murraya koenigii Leaf on Oxidative Stress and Cholinergic Transmission in Aged Mice. Phytotherapy Research. Assay: Alanine transaminase in mice serum.
rattan R et al (2011). Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity in vivo. Neoplasia 13(5):483-491. Assay: Alanine transaminase in mouse plasma.
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