Shopping Cart

Poly(ADP-Ribose) Polymerase Inhibitor Screening Service


Poly (ADP-Ribose) Polymerase or PARP (EC is involved in single-stranded DNA break repair. It is integral to a programmed cell death model based on caspase cleavage. PARP is composed of four domains of interest: a DNA-binding domain, a caspase-cleaved domain, an auto-modification domain, and a catalytic domain. The DNA-binding domain is composed of two zinc finger motifs. Inhibitors of PARP-1 are being studied in the treatment of cancer.

BioAssay Systems has developed a high-throughput screening assay for PARP inhibitors. Our Services includes, but not limited to:
  • PARP inhibitor hit profiling.
  • PARP Inhibitor lead generation.
  • Structure-activity relationship studies.
Please email or call us at 1-510-782-9988 x 2 to discuss your service needs.

Customer Testimonials